|
gptkbp:instanceOf
|
gptkb:disease
|
|
gptkbp:abbreviation
|
gptkb:ALS
|
|
gptkbp:affects
|
motor neurons
voluntary muscles
|
|
gptkbp:alsoKnownAs
|
amyotrophic lateral sclerosis
|
|
gptkbp:averageSurvivalAfterDiagnosis
|
2 to 5 years
|
|
gptkbp:cause
|
difficulty breathing
difficulty speaking
difficulty swallowing
muscle atrophy
muscle weakness
unknown in most cases
|
|
gptkbp:class
|
gptkb:neurodegenerative_disease
gptkb:motor_neuron_disease
|
|
gptkbp:diagnosedBy
|
gptkb:EMG
gptkb:neurological_examination
MRI
nerve conduction study
|
|
gptkbp:firstDescribed
|
gptkb:Jean-Martin_Charcot
1869
|
|
gptkbp:hasNoCure
|
true
|
|
gptkbp:hereditaryForm
|
gptkb:familial_ALS
|
|
gptkbp:ICD-10_code
|
G12.2
|
|
gptkbp:namedAfter
|
gptkb:Lou_Gehrig
|
|
gptkbp:notableCase
|
gptkb:Stephen_Hawking
gptkb:Steve_Gleason
gptkb:Lou_Gehrig
gptkb:Jason_Becker
|
|
gptkbp:onset
|
usually after age 40
|
|
gptkbp:prevalence
|
rare
|
|
gptkbp:prognosis
|
progressive and fatal
|
|
gptkbp:relatedTo
|
spinal muscular atrophy
primary lateral sclerosis
progressive muscular atrophy
|
|
gptkbp:riskFactor
|
gptkb:genetic_disorder
age
family history
male sex
|
|
gptkbp:sporadicForm
|
gptkb:sporadic_ALS
|
|
gptkbp:studiedBy
|
neurology
|
|
gptkbp:symptom
|
gptkb:pseudobulbar_affect
fatigue
weight loss
emotional lability
spasticity
muscle cramps
fasciculations
|
|
gptkbp:treatment
|
gptkb:edaravone
gptkb:riluzole
|
|
gptkbp:bfsParent
|
gptkb:Amyotrophic_lateral_sclerosis
|
|
gptkbp:bfsLayer
|
4
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Lou Gehrig's disease
|