Lou Gehrig's disease

GPTKB entity

Statements (52)
Predicate Object
gptkbp:instanceOf gptkb:disease
gptkbp:abbreviation gptkb:ALS
gptkbp:affects motor neurons
voluntary muscles
gptkbp:alsoKnownAs amyotrophic lateral sclerosis
gptkbp:averageSurvivalAfterDiagnosis 2 to 5 years
gptkbp:cause difficulty breathing
difficulty speaking
difficulty swallowing
muscle atrophy
muscle weakness
unknown in most cases
gptkbp:class neurodegenerative disease
motor neuron disease
gptkbp:diagnosedBy gptkb:EMG
neurological examination
MRI
nerve conduction study
gptkbp:firstDescribed gptkb:Jean-Martin_Charcot
1869
gptkbp:hasNoCure true
gptkbp:hereditaryForm gptkb:familial_ALS
https://www.w3.org/2000/01/rdf-schema#label Lou Gehrig's disease
gptkbp:ICD-10_code G12.2
gptkbp:namedAfter gptkb:Lou_Gehrig
gptkbp:notableCase gptkb:Stephen_Hawking
gptkb:Steve_Gleason
gptkb:Lou_Gehrig
gptkb:Jason_Becker
gptkbp:onset usually after age 40
gptkbp:prevalence rare
gptkbp:prognosis progressive and fatal
gptkbp:relatedTo spinal muscular atrophy
primary lateral sclerosis
progressive muscular atrophy
gptkbp:riskFactor age
family history
genetic disorder
male sex
gptkbp:sporadicForm gptkb:sporadic_ALS
gptkbp:studiedBy neurology
gptkbp:symptom gptkb:pseudobulbar_affect
fatigue
weight loss
emotional lability
spasticity
muscle cramps
fasciculations
gptkbp:treatment gptkb:edaravone
gptkb:riluzole
gptkbp:bfsParent gptkb:Amyotrophic_lateral_sclerosis
gptkbp:bfsLayer 4