gptkbp:instanceOf
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gptkb:disease
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gptkbp:abbreviation
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gptkb:ALS
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gptkbp:affects
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motor neurons
voluntary muscles
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gptkbp:alsoKnownAs
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amyotrophic lateral sclerosis
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gptkbp:averageSurvivalAfterDiagnosis
|
2 to 5 years
|
gptkbp:cause
|
difficulty breathing
difficulty speaking
difficulty swallowing
muscle atrophy
muscle weakness
unknown in most cases
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gptkbp:class
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neurodegenerative disease
motor neuron disease
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gptkbp:diagnosedBy
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gptkb:EMG
neurological examination
MRI
nerve conduction study
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gptkbp:firstDescribed
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gptkb:Jean-Martin_Charcot
1869
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gptkbp:hasNoCure
|
true
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gptkbp:hereditaryForm
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gptkb:familial_ALS
|
https://www.w3.org/2000/01/rdf-schema#label
|
Lou Gehrig's disease
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gptkbp:ICD-10_code
|
G12.2
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gptkbp:namedAfter
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gptkb:Lou_Gehrig
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gptkbp:notableCase
|
gptkb:Stephen_Hawking
gptkb:Steve_Gleason
gptkb:Lou_Gehrig
gptkb:Jason_Becker
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gptkbp:onset
|
usually after age 40
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gptkbp:prevalence
|
rare
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gptkbp:prognosis
|
progressive and fatal
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gptkbp:relatedTo
|
spinal muscular atrophy
primary lateral sclerosis
progressive muscular atrophy
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gptkbp:riskFactor
|
age
family history
genetic disorder
male sex
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gptkbp:sporadicForm
|
gptkb:sporadic_ALS
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gptkbp:studiedBy
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neurology
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gptkbp:symptom
|
gptkb:pseudobulbar_affect
fatigue
weight loss
emotional lability
spasticity
muscle cramps
fasciculations
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gptkbp:treatment
|
gptkb:edaravone
gptkb:riluzole
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gptkbp:bfsParent
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gptkb:Amyotrophic_lateral_sclerosis
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gptkbp:bfsLayer
|
4
|