Alzheimer's disease (genetic association studies)
GPTKB entity
Statements (55)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic association study
|
| gptkbp:associatedWith |
gptkb:CR1_gene
gptkb:APOE_gene gptkb:ACE_gene gptkb:CD33_gene gptkb:CELF1_gene gptkb:CLU_gene gptkb:PICALM_gene gptkb:PSEN1_gene gptkb:PSEN2_gene gptkb:TREM2_gene gptkb:APP_gene MEF2C gene ABCA7 gene BIN1 gene CASS4 gene CD2AP gene DSG2 gene EPHA1 gene FERMT2 gene HLA-DRB5/HLA-DRB1 region INPP5D gene MS4A6A gene NME8 gene PTK2B gene SLC24A4 gene SORL1 gene ZCWPW1 gene |
| gptkbp:contributedTo |
polygenic risk score
|
| gptkbp:focusesOn |
genome-wide association studies
|
| gptkbp:goal |
identify genetic variants
improve risk prediction inform drug development understand heritability |
| https://www.w3.org/2000/01/rdf-schema#label |
Alzheimer's disease (genetic association studies)
|
| gptkbp:method |
meta-analysis
linkage analysis candidate gene study case-control study |
| gptkbp:publishedIn |
gptkb:Nature_Genetics
gptkb:Journal_of_Alzheimer's_Disease gptkb:The_Lancet_Neurology Alzheimer's & Dementia |
| gptkbp:recognizedBy |
susceptibility loci
|
| gptkbp:relatedTo |
gptkb:late-onset_Alzheimer's_disease
gptkb:familial_Alzheimer's_disease early-onset Alzheimer's disease sporadic Alzheimer's disease |
| gptkbp:studies |
genetic risk factors
|
| gptkbp:supports |
gptkb:National_Institute_on_Aging
Alzheimer's Disease Genetics Consortium International Genomics of Alzheimer's Project |
| gptkbp:topic |
gptkb:Alzheimer's_disease
|
| gptkbp:bfsParent |
gptkb:MS4A6A
|
| gptkbp:bfsLayer |
8
|