familial Alzheimer's disease
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genetic disorder
form of Alzheimer's disease |
| gptkbp:alsoKnownAs |
gptkb:FAD
|
| gptkbp:associatedWith |
amyloid plaques
neurofibrillary tangles |
| gptkbp:cause |
mutations in APP gene
mutations in PSEN1 gene mutations in PSEN2 gene |
| gptkbp:diagnosedBy |
genetic testing
|
| gptkbp:field |
neurology
|
| gptkbp:firstDescribed |
early 20th century
|
| gptkbp:frequency |
rare
|
| https://www.w3.org/2000/01/rdf-schema#label |
familial Alzheimer's disease
|
| gptkbp:inheritance |
autosomal dominant
|
| gptkbp:onset |
early onset
|
| gptkbp:progression |
progressive neurodegeneration
|
| gptkbp:proportion_of_Alzheimer's_cases |
less than 1%
|
| gptkbp:riskFactor |
family history of Alzheimer's disease
|
| gptkbp:symptom |
cognitive decline
memory loss |
| gptkbp:treatment |
symptomatic management
|
| gptkbp:bfsParent |
gptkb:Amyloid_beta_A4_protein
|
| gptkbp:bfsLayer |
7
|