Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genomics technique
|
| gptkbp:analyzes |
DNA-protein interactions
|
| gptkbp:developedBy |
2000s
|
| gptkbp:fullName |
Micrococcal Nuclease sequencing
|
| gptkbp:hasBiologicalActivity |
gptkb:micrococcal_nuclease
|
| https://www.w3.org/2000/01/rdf-schema#label |
MNase-seq
|
| gptkbp:limitation |
sequence bias of MNase
cannot distinguish between nucleosome-free and protein-bound regions without further analysis |
| gptkbp:relatedTo |
gptkb:ATAC-seq
ChIP-seq |
| gptkbp:studies |
chromatin accessibility
nucleosome positioning nucleosome occupancy |
| gptkbp:supportsProtocol |
high-throughput sequencing
digestion of chromatin with MNase isolation of mononucleosomal DNA |
| gptkbp:type |
eukaryotic cells
sequencing reads nucleosome maps |
| gptkbp:usedFor |
mapping nucleosome positions
studying chromatin structure |
| gptkbp:bfsParent |
gptkb:ATAC-seq
|
| gptkbp:bfsLayer |
7
|