Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
single-cell sequencing technique
|
| gptkbp:analyzes |
regulatory elements
open chromatin regions |
| gptkbp:bioinformaticsTools |
gptkb:Cicero
gptkb:ArchR gptkb:Seurat gptkb:Signac Cell Ranger ATAC SnapATAC chromVAR |
| gptkbp:combines |
scRNA-seq
CITE-seq multiome sequencing |
| gptkbp:commercialPlatforms |
gptkb:Bio-Rad
gptkb:10x_Genomics gptkb:Mission_Bio |
| gptkbp:developedBy |
gptkb:ATAC-seq
|
| gptkbp:enables |
study of gene regulation
cell type identification identification of cis-regulatory elements integration with transcriptomic data study of cellular heterogeneity study of transcription factor binding |
| gptkbp:firstPublished |
2015
|
| gptkbp:fullName |
single-cell Assay for Transposase-Accessible Chromatin using sequencing
|
| https://www.w3.org/2000/01/rdf-schema#label |
scATAC-seq
|
| gptkbp:limitation |
high cost
sparse data complex data analysis technical noise |
| gptkbp:output |
cell-by-peak matrix
fragment counts peak matrices |
| gptkbp:relatedTo |
scRNA-seq
single-cell multiomics |
| gptkbp:supportsProtocol |
sequencing
library preparation transposition cell isolation bioinformatic analysis |
| gptkbp:type |
DNA sequencing
|
| gptkbp:usedFor |
epigenomics
single-cell analysis chromatin accessibility profiling |
| gptkbp:usedIn |
cancer research
developmental biology immunology neuroscience |
| gptkbp:uses |
gptkb:Tn5_transposase
|
| gptkbp:bfsParent |
gptkb:ATAC-seq
|
| gptkbp:bfsLayer |
7
|