Assay for Transposase-Accessible Chromatin using sequencing

URI: https://gptkb.org/entity/Assay_for_Transposase-Accessible_Chromatin_using_sequencing
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf genomics technique
gptkbp:abbreviation gptkb:ATAC-seq
gptkbp:advantage fast protocol
requires low cell number
gptkbp:analyzes open chromatin regions
gptkbp:application epigenomics
transcription factor binding site identification
nucleosome positioning
gptkbp:contrastsWith gptkb:FAIRE-seq
DNase-seq
gptkbp:data_analysis motif analysis
peak calling
gptkbp:developedBy gptkb:Jason_D._Buenrostro
https://www.w3.org/2000/01/rdf-schema#label Assay for Transposase-Accessible Chromatin using sequencing
gptkbp:introducedIn 2013
gptkbp:output sequencing reads
gptkbp:protocol_step next-generation sequencing
PCR amplification
cell lysis
transposase treatment
gptkbp:publishedIn gptkb:Nature_Methods
gptkbp:relatedTo gptkb:MNase-seq
ChIP-seq
gptkbp:used_in cancer research
developmental biology
immunology
neuroscience
gptkbp:usedFor chromatin accessibility profiling
gptkbp:uses_enzyme gptkb:Tn5_transposase
gptkbp:variant gptkb:multiome_ATAC-seq
gptkb:single-cell_ATAC-seq
gptkbp:bfsParent gptkb:ATAC-seq
gptkbp:bfsLayer 7