Statements (53)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genomic assay
|
| gptkbp:advantage |
fast protocol
requires low input material |
| gptkbp:analyzes |
open chromatin regions
|
| gptkbp:application |
epigenomics
disease research single-cell analysis gene regulation studies |
| gptkbp:citation |
Buenrostro JD et al., Nature Methods, 2013
|
| gptkbp:contrastsWith |
gptkb:DNase-Seq
FAIRE-Seq |
| gptkbp:dataAnalysis |
motif analysis
peak calling differential accessibility analysis |
| gptkbp:dataAnalysisTool |
gptkb:ArchR
gptkb:MACS2 gptkb:Signac HOMER SnapATAC |
| gptkbp:developedBy |
gptkb:Jason_D._Buenrostro
2013 |
| gptkbp:enables |
identification of regulatory elements
nucleosome positioning analysis transcription factor footprinting |
| gptkbp:fullName |
gptkb:Assay_for_Transposase-Accessible_Chromatin_using_sequencing
|
| gptkbp:hasBiologicalActivity |
gptkb:Tn5_transposase
|
| https://www.w3.org/2000/01/rdf-schema#label |
ATAC-Seq
|
| gptkbp:limitation |
mitochondrial DNA contamination
sequence bias requires fresh or properly preserved samples |
| gptkbp:output |
FASTQ files
|
| gptkbp:publishedIn |
gptkb:Nature_Methods
|
| gptkbp:relatedTo |
gptkb:ChIP-Seq
MNase-Seq |
| gptkbp:sequencingPlatform |
gptkb:Illumina
gptkb:BGI |
| gptkbp:supportsProtocol |
sequencing
library preparation PCR amplification transposition cell lysis |
| gptkbp:type |
next-generation sequencing
|
| gptkbp:usedFor |
chromatin accessibility profiling
|
| gptkbp:usedIn |
gptkb:human
gptkb:mouse gptkb:plant_species gptkb:yeast |
| gptkbp:variant |
ATAC-see
Omni-ATAC scATAC-Seq single-cell ATAC-Seq |
| gptkbp:bfsParent |
gptkb:ChIP-Seq
|
| gptkbp:bfsLayer |
7
|