|
gptkbp:instanceOf
|
gptkb:genomic_assay
|
|
gptkbp:advantage
|
fast protocol
requires low input material
|
|
gptkbp:analyzes
|
open chromatin regions
|
|
gptkbp:application
|
epigenomics
disease research
single-cell analysis
gene regulation studies
|
|
gptkbp:citation
|
Buenrostro JD et al., Nature Methods, 2013
|
|
gptkbp:contrastsWith
|
gptkb:DNase-Seq
FAIRE-Seq
|
|
gptkbp:dataAnalysis
|
motif analysis
peak calling
differential accessibility analysis
|
|
gptkbp:dataAnalysisTool
|
gptkb:ArchR
gptkb:MACS2
gptkb:Signac
HOMER
SnapATAC
|
|
gptkbp:developedBy
|
gptkb:Jason_D._Buenrostro
2013
|
|
gptkbp:enables
|
identification of regulatory elements
nucleosome positioning analysis
transcription factor footprinting
|
|
gptkbp:fullName
|
gptkb:Assay_for_Transposase-Accessible_Chromatin_using_sequencing
|
|
gptkbp:hasBiologicalActivity
|
gptkb:Tn5_transposase
|
|
gptkbp:limitation
|
mitochondrial DNA contamination
sequence bias
requires fresh or properly preserved samples
|
|
gptkbp:output
|
FASTQ files
|
|
gptkbp:publishedIn
|
gptkb:Nature_Methods
|
|
gptkbp:relatedTo
|
gptkb:ChIP-Seq
MNase-Seq
|
|
gptkbp:sequencingPlatform
|
gptkb:Illumina
gptkb:BGI
|
|
gptkbp:supportsProtocol
|
sequencing
library preparation
PCR amplification
transposition
cell lysis
|
|
gptkbp:type
|
next-generation sequencing
|
|
gptkbp:usedFor
|
chromatin accessibility profiling
|
|
gptkbp:usedIn
|
gptkb:human
gptkb:mouse
gptkb:plant_species
gptkb:yeast
|
|
gptkbp:variant
|
ATAC-see
Omni-ATAC
scATAC-Seq
single-cell ATAC-Seq
|
|
gptkbp:bfsParent
|
gptkb:ChIP-Seq
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ATAC-Seq
|