Statements (54)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
genomics technique
|
| gptkbp:alternativeTo |
gptkb:ChIP-chip
|
| gptkbp:analyzes |
gptkb:MACS
gptkb:SICER HOMER DNA fragments bound to proteins peak calling algorithms |
| gptkbp:combines |
next-generation sequencing
chromatin immunoprecipitation |
| gptkbp:developedBy |
2007
|
| gptkbp:enables |
identification of regulatory elements
study of gene regulation study of chromatin structure |
| gptkbp:format |
gptkb:FASTQ
gptkb:BED BAM |
| gptkbp:fullName |
gptkb:Chromatin_Immunoprecipitation_Sequencing
|
| https://www.w3.org/2000/01/rdf-schema#label |
ChIP-Seq
|
| gptkbp:limitation |
gptkb:government_agency
background noise antibody specificity sequencing depth |
| gptkbp:output |
genome-wide binding profiles
|
| gptkbp:publishedIn |
gptkb:Nature_Methods
gptkb:Genome_Research |
| gptkbp:recognizedBy |
transcription factor binding sites
chromatin-associated protein binding sites histone modification sites |
| gptkbp:relatedTo |
gptkb:ATAC-Seq
gptkb:DNase-Seq RNA-Seq |
| gptkbp:requires |
data analysis
sequencing bioinformatics analysis library preparation immunoprecipitation DNA purification antibody specific to protein of interest crosslinking of proteins to DNA fragmentation of chromatin |
| gptkbp:type |
high-throughput sequencing data
|
| gptkbp:usedBy |
geneticists
bioinformaticians molecular biologists |
| gptkbp:usedFor |
identifying DNA-protein interactions
mapping binding sites of DNA-associated proteins |
| gptkbp:usedIn |
cancer research
developmental biology stem cell research epigenetics histone modification analysis transcription factor binding studies |
| gptkbp:bfsParent |
gptkb:HiSeq
|
| gptkbp:bfsLayer |
6
|