Statements (18)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:aminoAcidChange |
Cys112, Cys158
|
| gptkbp:associatedWith |
gptkb:type_III_hyperlipoproteinemia
lower risk of Alzheimer's disease |
| gptkbp:distinctFrom |
gptkb:APOE-e3
gptkb:APOE-e4 |
| gptkbp:effectOnLipidMetabolism |
reduced binding to LDL receptor
|
| gptkbp:encodes |
gptkb:apolipoprotein_E2
|
| gptkbp:frequency |
~8% (varies by ethnicity)
|
| gptkbp:gene |
gptkb:APOE
|
| gptkbp:hasSNP |
gptkb:rs7412
|
| https://www.w3.org/2000/01/rdf-schema#label |
APOE-e2
|
| gptkbp:locatedOnChromosome |
chromosome 19q13.32
|
| gptkbp:protectiveEffect |
gptkb:Alzheimer's_disease
|
| gptkbp:riskFactor |
gptkb:type_III_hyperlipoproteinemia
|
| gptkbp:variant |
gptkb:APOE
|
| gptkbp:bfsParent |
gptkb:APOE-e4_allele
|
| gptkbp:bfsLayer |
5
|