APC (adenomatous polyposis coli)
GPTKB entity
Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:associatedWith |
gptkb:familial_adenomatous_polyposis
colorectal cancer |
| gptkbp:discoveredBy |
gptkb:Bert_Vogelstein
|
| gptkbp:encodes |
gptkb:APC_protein
|
| gptkbp:Entrez_Gene_ID |
324
|
| gptkbp:expressedIn |
gptkb:small_intestine
colon |
| gptkbp:function |
tumor suppressor
|
| gptkbp:HGNC_ID |
HGNC:583
|
| https://www.w3.org/2000/01/rdf-schema#label |
APC (adenomatous polyposis coli)
|
| gptkbp:inhibitedBy |
gptkb:Wnt_signaling_pathway
|
| gptkbp:interactsWith |
gptkb:beta-catenin
|
| gptkbp:length |
2843 amino acids
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_5
5q22.2 |
| gptkbp:mutationAssociatedWith |
polyps in colon
|
| gptkbp:OMIM |
611731
|
| gptkbp:orthologInMouse |
Apc
|
| gptkbp:UniProtID |
P25054
|
| gptkbp:bfsParent |
gptkb:APC2
|
| gptkbp:bfsLayer |
7
|