Statements (55)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:ALB_HUMAN
gptkb:Human_serum_albumin gptkb:Serum_albumin Albumin |
| gptkbp:associatedWith |
analbuminemia
familial dysalbuminemic hyperthyroxinemia |
| gptkbp:binds |
drugs
thyroid hormones fatty acids bilirubin metal ions |
| gptkbp:disulfideBond |
17
|
| gptkbp:domain |
three homologous domains
|
| gptkbp:EC_number |
nan
|
| gptkbp:expressedIn |
high in liver
present in plasma |
| gptkbp:family |
gptkb:albumin_family
|
| gptkbp:fullName |
gptkb:Serum_albumin
|
| gptkbp:function |
maintains oncotic pressure
transports drugs transports fatty acids transports hormones |
| gptkbp:gene |
gptkb:ALB
|
| gptkbp:glycosylation |
not glycosylated
|
| gptkbp:hasIsoform |
1
|
| https://www.w3.org/2000/01/rdf-schema#label |
ALBU HUMAN
|
| gptkbp:length |
609 amino acids
|
| gptkbp:locatedOnChromosome |
4q13.3
|
| gptkbp:location |
extracellular region
|
| gptkbp:massSpectrometry |
detected in plasma
|
| gptkbp:molecularWeight |
69 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
gptkb:1AO6
gptkb:1BM0 gptkb:2BXG gptkb:4K2C gptkb:1UOR 1E7I 6EZQ |
| gptkbp:postTranslationalModification |
gptkb:N-terminal_acetylation
phosphorylation oxidation |
| gptkbp:products |
no
|
| gptkbp:sequence |
MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIAFAQYLQQCPFEDHVKLVNEVTEFAKTCVADESAENCDKSLHTLFGDKLCTVATLRETYGEMADCCAKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLFFAKRYKAAFTECCQAADKAACLLPKLDELRDEGKASSAKQRLKCASLQKFGERAFKAWAVARLSQRFPKAEFAEVSKLVTDLTKVHTECCHGDLLECADDRADLAKYICDNQDTISSKLELQKHKPKATKEQLKAVMDDFAAFVEKCCKADDKETCFAEEGKKLVAASQAALGL
|
| gptkbp:sequenceStatus |
complete
|
| gptkbp:significance |
hypoalbuminemia in liver disease
marker for liver function used in drug binding studies |
| gptkbp:subcellularLocation |
secreted
|
| gptkbp:tissue_specificity |
liver
|
| gptkbp:UniProtID |
gptkb:P02768
|
| gptkbp:uniprotReviewed |
yes
|
| gptkbp:bfsParent |
gptkb:P22303
|
| gptkbp:bfsLayer |
7
|