Statements (53)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:abbreviation |
gptkb:HSA
|
gptkbp:allergenicity |
low
|
gptkbp:alternativeName |
gptkb:serum_albumin
albumin |
gptkbp:binds |
gptkb:water
copper zinc drugs calcium ions magnesium hormones thyroxine fatty acids bilirubin |
gptkbp:degradedBy |
gptkb:kidney
|
gptkbp:discoveredBy |
gptkb:Osborne_and_Harris
|
gptkbp:discoveredIn |
1934
|
gptkbp:encodedBy |
gptkb:ALB_gene
|
gptkbp:foundIn |
human blood plasma
|
gptkbp:function |
buffers pH
maintains oncotic pressure transports bilirubin transports drugs transports fatty acids transports hormones |
gptkbp:halfLife |
about 19 days
|
gptkbp:HGNC_ID |
399
|
https://www.w3.org/2000/01/rdf-schema#label |
Human serum albumin
|
gptkbp:length |
585
|
gptkbp:locatedOnChromosome |
4q13.3
|
gptkbp:medicalUse |
treatment of burns
treatment of hypoalbuminemia treatment of liver disease treatment of nephrotic syndrome treatment of shock volume expander |
gptkbp:molecularWeight |
66.5 kDa
|
gptkbp:OMIM |
103600
|
gptkbp:PDB |
gptkb:1AO6
|
gptkbp:pI |
4.7
|
gptkbp:range |
3.5–5.0 g/dL (serum)
|
gptkbp:structure |
single polypeptide chain
|
gptkbp:synthesisType |
liver
|
gptkbp:UniProtID |
gptkb:P02768
|
gptkbp:usedIn |
biochemical research
vaccine production diagnostic reagents cell culture media drug formulation |
gptkbp:bfsParent |
gptkb:P22303
|
gptkbp:bfsLayer |
7
|