|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:clinicalBiomarker
|
Serum albumin level used as a biomarker for liver and kidney function
|
|
gptkbp:disorderAssociated
|
gptkb:Analbuminemia
|
|
gptkbp:drugBinding
|
Binds diazepam
Binds ibuprofen
Binds penicillin
Binds salicylate
Binds warfarin
|
|
gptkbp:EC_number
|
nan
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000163631
213
|
|
gptkbp:expressedIn
|
Highly expressed in liver
|
|
gptkbp:fullName
|
gptkb:Serum_albumin
|
|
gptkbp:function
|
Maintains oncotic pressure of blood
Binds to water, cations, fatty acids, hormones, bilirubin, and drugs
Transports hormones, fatty acids, and other compounds
|
|
gptkbp:gene
|
gptkb:ALB
|
|
gptkbp:GO_term
|
gptkb:GO:0006953_(acute-phase_response)
gptkb:GO:0019835_(cytokine_binding)
gptkb:GO:0034774_(secretory_granule_lumen)
gptkb:GO:0070062_(extracellular_exosome)
GO:0005615 (extracellular space)
GO:0006879 (cellular iron ion homeostasis)
GO:0046872 (metal ion binding)
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ALB HUMAN
|
|
gptkbp:length
|
609 amino acids
|
|
gptkbp:locatedOnChromosome
|
4
|
|
gptkbp:location
|
4q13.3
|
|
gptkbp:molecularWeight
|
69.3 kDa
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Alb_MOUSE
Alb_BOVIN
Alb_RAT
|
|
gptkbp:pathway
|
Transport of small molecules
Platelet degranulation
Lipoprotein metabolism
|
|
gptkbp:PDB
|
gptkb:1AO6
gptkb:1BM0
1E7I
|
|
gptkbp:postTranslationalModification
|
Disulfide bonds
Glycosylated
Phosphorylated
|
|
gptkbp:products
|
No alternative isoforms
|
|
gptkbp:proteinFamily
|
gptkb:Albumins
|
|
gptkbp:RefSeq
|
gptkb:NM_000477
|
|
gptkbp:reviewedBy
|
Yes
|
|
gptkbp:sequenceStatus
|
Complete
|
|
gptkbp:structure
|
Contains 3 homologous domains
|
|
gptkbp:subcellularLocation
|
Secreted
|
|
gptkbp:tissue_specificity
|
Liver
|
|
gptkbp:UniProt_entry_name
|
gptkb:ALBU_HUMAN
|
|
gptkbp:UniProtID
|
gptkb:P02768
|
|
gptkbp:bfsParent
|
gptkb:P22303
|
|
gptkbp:bfsLayer
|
7
|