|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:BHLHE2
gptkb:HIF-1β-like_factor
|
|
gptkbp:alternativeName
|
gptkb:Class_E_basic_helix-loop-helix_protein_2
gptkb:HIF-1_beta-like_factor
gptkb:bHLHe2
|
|
gptkbp:biologicalProcess
|
DNA binding
protein dimerization activity
|
|
gptkbp:discoveredBy
|
Jiang et al.
|
|
gptkbp:discoveredIn
|
1996
|
|
gptkbp:encodes
|
gptkb:Aryl_hydrocarbon_receptor_nuclear_translocator_2_protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000172379
9915
|
|
gptkbp:expressedIn
|
gptkb:kidney
brain
pancreas
hypothalamus
|
|
gptkbp:fullName
|
gptkb:Aryl_hydrocarbon_receptor_nuclear_translocator_2
|
|
gptkbp:function
|
transcription factor
dimerizes with bHLH-PAS proteins
|
|
gptkbp:GO_term
|
GO:0003700
GO:0006355
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:700
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ARNT2
|
|
gptkbp:involvedIn
|
neuronal development
circadian rhythm regulation
hypoxia response
|
|
gptkbp:length
|
717
|
|
gptkbp:locatedOnChromosome
|
15
|
|
gptkbp:location
|
gptkb:15q24.1
|
|
gptkbp:molecularWeight
|
78 kDa
|
|
gptkbp:mutationAssociatedWith
|
neurodevelopmental disorders
hypothalamic dysfunction
|
|
gptkbp:OMIM
|
602272
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:mouse_Arnt2
gptkb:rat_Arnt2
|
|
gptkbp:proteinFamily
|
gptkb:bHLH-PAS
|
|
gptkbp:RefSeq
|
gptkb:NM_014862
gptkb:NP_055104
|
|
gptkbp:regulates
|
neuronal gene expression
transcription of hypoxia-inducible genes
|
|
gptkbp:relatedTo
|
gptkb:SIM1
gptkb:AHR
gptkb:NPAS4
gptkb:HIF1A
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
gptkb:Q9HBZ2
|
|
gptkbp:bfsParent
|
gptkb:SIM1
|
|
gptkbp:bfsLayer
|
6
|