|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeTo
|
gptkb:AT2
AT2R
G-Protein Coupled Receptor 1B
|
|
gptkbp:associatedWith
|
hypertension
congenital urinary tract malformations
|
|
gptkbp:biologicalProcess
|
blood pressure regulation
cardiovascular development
renal development
angiotensin receptor activity
|
|
gptkbp:discoveredIn
|
1993
|
|
gptkbp:encodes
|
angiotensin II receptor type 2 protein
|
|
gptkbp:enemyOf
|
CGP42112A
PD123319
|
|
gptkbp:Entrez_Gene_ID
|
186
ENSG00000180772
|
|
gptkbp:expressedIn
|
gptkb:adrenal_gland
heart
uterus
fetal tissues
|
|
gptkbp:fullName
|
angiotensin II receptor type 2
|
|
gptkbp:function
|
mediates effects of angiotensin II
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasPhenotype
|
X-linked mental retardation
intellectual disability (in some mutations)
|
|
gptkbp:HGNC_ID
|
333
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AGTR2 gene
|
|
gptkbp:length
|
363
|
|
gptkbp:locatedOnChromosome
|
X
|
|
gptkbp:location
|
Xq23
|
|
gptkbp:molecularWeight
|
41 kDa
|
|
gptkbp:OMIM
|
300034
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
Agtr2
|
|
gptkbp:pathway
|
gptkb:Renin-angiotensin_system
|
|
gptkbp:proteinFamily
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:regulates
|
apoptosis
cell growth
vasodilation
|
|
gptkbp:relatedTo
|
gptkb:AGTR1_gene
|
|
gptkbp:reviewedBy
|
gptkb:GeneReviews
gptkb:UniProtKB/Swiss-Prot
gptkb:OMIM
|
|
gptkbp:transmembraneDomains
|
7
|
|
gptkbp:UniProtID
|
P50052
|
|
gptkbp:bfsParent
|
gptkb:angiotensin_receptor
|
|
gptkbp:bfsLayer
|
6
|