Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
A Disintegrin And Metalloproteinase
ADAM proteins |
| gptkbp:associatedWith |
gptkb:cancer
neurodegenerative diseases inflammatory diseases |
| gptkbp:biologicalProcess |
development
immune response neurogenesis fertilization ectodomain shedding |
| gptkbp:catalyzes |
zinc-dependent protease
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:domain |
cysteine-rich domain
transmembrane domain EGF-like domain cytoplasmic tail disintegrin domain metalloprotease domain |
| gptkbp:example |
gptkb:ADAM17
gptkb:ADAM12 ADAM10 ADAM8 ADAM9 |
| gptkbp:foundIn |
animals
|
| gptkbp:fullName |
A Disintegrin And Metalloprotease
|
| gptkbp:function |
cell signaling
cell adhesion proteolysis |
| https://www.w3.org/2000/01/rdf-schema#label |
ADAM metalloproteases
|
| gptkbp:proteinFamily |
gptkb:ADAM
|
| gptkbp:relatedTo |
gptkb:ADAMTS_family
gptkb:matrix_metalloproteinases |
| gptkbp:bfsParent |
gptkb:HB-EGF
|
| gptkbp:bfsLayer |
7
|