Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
peptide
|
| gptkbp:accumulatesIn |
extracellular space
|
| gptkbp:aggregationPropensity |
high
|
| gptkbp:associatedWith |
gptkb:Alzheimer's_disease
|
| gptkbp:cause |
synaptic dysfunction
|
| gptkbp:cleavage |
gptkb:beta-secretase
gptkb:gamma-secretase |
| gptkbp:derivedFrom |
Amyloid precursor protein (APP)
|
| gptkbp:firstDescribed |
1992
|
| gptkbp:form |
amyloid plaques
|
| gptkbp:foundIn |
brain
|
| gptkbp:fullName |
Amyloid beta 42
|
| gptkbp:hasIsoform |
gptkb:Aβ40
|
| https://www.w3.org/2000/01/rdf-schema#label |
Aβ42
|
| gptkbp:involves |
neurodegeneration
|
| gptkbp:length |
42 amino acids
|
| gptkbp:relatedTo |
gptkb:Aβ40
|
| gptkbp:sequence |
DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
|
| gptkbp:studiedIn |
gptkb:transgenic_mouse_models
|
| gptkbp:toxicity |
neurons
|
| gptkbp:UniProtID |
P05067-3
|
| gptkbp:bfsParent |
gptkb:amyloid_beta_protein
|
| gptkbp:bfsLayer |
7
|