Statements (32)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:receptor_tyrosine_kinase
gptkb:G_protein-coupled_receptor |
gptkbp:activatedBy |
gptkb:adenylate_cyclase
|
gptkbp:affects |
cardiac contractility
dopamine release GABA release acetylcholine release |
gptkbp:alternativeSplicing |
multiple isoforms
|
gptkbp:binds |
serotonin
|
gptkbp:couplingType |
gptkb:Gs_protein
|
gptkbp:discoveredIn |
1992
|
gptkbp:encodedBy |
HTR4 gene
|
gptkbp:enemyOf |
gptkb:prucalopride
gptkb:cisapride GR 113808 RS-39604 SB-204070 tegaserod |
gptkbp:expressedIn |
gptkb:human
gptkb:mouse right |
gptkbp:foundIn |
gastrointestinal tract
central nervous system |
https://www.w3.org/2000/01/rdf-schema#label |
5-HT4 receptor
|
gptkbp:modulatedBy |
cognitive function
gastrointestinal motility cardiac function |
gptkbp:target |
antidepressant research
irritable bowel syndrome treatment prokinetic drugs |
gptkbp:bfsParent |
gptkb:receptor_tyrosine_kinase
|
gptkbp:bfsLayer |
6
|