5-HT4 receptor

GPTKB entity

Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:receptor_tyrosine_kinase
gptkb:G_protein-coupled_receptor
gptkbp:activatedBy gptkb:adenylate_cyclase
gptkbp:affects cardiac contractility
dopamine release
GABA release
acetylcholine release
gptkbp:alternativeSplicing multiple isoforms
gptkbp:binds serotonin
gptkbp:couplingType gptkb:Gs_protein
gptkbp:discoveredIn 1992
gptkbp:encodedBy HTR4 gene
gptkbp:enemyOf gptkb:prucalopride
gptkb:cisapride
GR 113808
RS-39604
SB-204070
tegaserod
gptkbp:expressedIn gptkb:human
gptkb:mouse
right
gptkbp:foundIn gastrointestinal tract
central nervous system
https://www.w3.org/2000/01/rdf-schema#label 5-HT4 receptor
gptkbp:modulatedBy cognitive function
gastrointestinal motility
cardiac function
gptkbp:target antidepressant research
irritable bowel syndrome treatment
prokinetic drugs
gptkbp:bfsParent gptkb:receptor_tyrosine_kinase
gptkbp:bfsLayer 6