Statements (26)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:chemical_compound
antineoplastic agent vinca alkaloid |
| gptkbp:administeredBy |
intravenous injection
|
| gptkbp:ATCCode |
L01CA04
|
| gptkbp:CASNumber |
53643-48-4
|
| gptkbp:derivedFrom |
gptkb:Catharanthus_roseus
|
| gptkbp:discoveredBy |
1973
|
| gptkbp:drugClass |
antimitotic agent
|
| gptkbp:hasMolecularFormula |
C43H55N5O7
|
| https://www.w3.org/2000/01/rdf-schema#label |
vindesine
|
| gptkbp:inhibitedBy |
microtubule formation
|
| gptkbp:IUPACName |
methyl (5β,12β,19α)-15-ethyl-5,12-dihydroxy-19-(methoxycarbonyl)-3,13-diazapentacyclo[14.2.2.0²,⁷.0⁸,¹³.0¹⁶,²⁰]icosa-1(18),2(7),3,5,8(13),9,11,16(20),17-nonaene-6-carboxylate
|
| gptkbp:marketedAs |
gptkb:Eldisine
|
| gptkbp:sideEffect |
nausea
vomiting constipation alopecia neurotoxicity myelosuppression |
| gptkbp:usedFor |
gptkb:non-small_cell_lung_cancer
gptkb:cancer leukemia malignant melanoma |
| gptkbp:bfsParent |
gptkb:vinblastine
|
| gptkbp:bfsLayer |
7
|