vascular endothelial growth factor (VEGF) family
GPTKB entity
Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:VEGF_family
|
| gptkbp:associatedWith |
gptkb:cancer
age-related macular degeneration diabetic retinopathy |
| gptkbp:binds |
VEGF receptor 1 (VEGFR-1)
VEGF receptor 2 (VEGFR-2) VEGF receptor 3 (VEGFR-3) |
| gptkbp:discoveredBy |
1989
|
| gptkbp:expressedIn |
endothelial cells
|
| gptkbp:function |
regulation of angiogenesis
regulation of lymphangiogenesis regulation of vasculogenesis |
| https://www.w3.org/2000/01/rdf-schema#label |
vascular endothelial growth factor (VEGF) family
|
| gptkbp:includes |
gptkb:VEGF-A
gptkb:VEGF-B gptkb:VEGF-E gptkb:VEGF-C gptkb:VEGF-D placenta growth factor (PlGF) |
| gptkbp:proteinFamily |
VEGF gene family
|
| gptkbp:regulates |
gptkb:hypoxia-inducible_factor_(HIF)
|
| gptkbp:target |
gptkb:bevacizumab
gptkb:aflibercept gptkb:ranibizumab |
| gptkbp:bfsParent |
gptkb:placental_growth_factor_(PlGF)
|
| gptkbp:bfsLayer |
7
|