|
gptkbp:instanceOf
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gptkb:virus
|
|
gptkbp:abbreviation
|
gptkb:VZV
|
|
gptkbp:antiviral_treatment
|
gptkb:famciclovir
gptkb:valacyclovir
gptkb:acyclovir
|
|
gptkbp:associatedWith
|
gptkb:varicella
herpes zoster
|
|
gptkbp:Baltimore_classification
|
Group I (dsDNA viruses)
|
|
gptkbp:capsid_symmetry
|
T=16
|
|
gptkbp:cause
|
gptkb:chickenpox
shingles
|
|
gptkbp:cell_entry_receptor
|
gptkb:myelin-associated_glycoprotein
gptkb:insulin-degrading_enzyme
gptkb:mannose_6-phosphate_receptor
|
|
gptkbp:discoveredBy
|
gptkb:Thomas_Huckle_Weller
|
|
gptkbp:discoveredIn
|
1952
|
|
gptkbp:DNA_length
|
about 125 kb
|
|
gptkbp:enveloped
|
true
lipid bilayer
|
|
gptkbp:family
|
gptkb:Herpesviridae
|
|
gptkbp:firstIsolatedFrom
|
vesicular fluid of chickenpox lesions
|
|
gptkbp:genomeType
|
double-stranded DNA
|
|
gptkbp:genus
|
gptkb:Varicellovirus
|
|
gptkbp:hostedBy
|
gptkb:human
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
varicella-zoster virus
|
|
gptkbp:infects
|
humans only
|
|
gptkbp:latency
|
established in dorsal root ganglia
|
|
gptkbp:latent_infection_site
|
sensory ganglia
|
|
gptkbp:notable_for
|
glycoprotein B
glycoprotein E
glycoprotein I
|
|
gptkbp:numberOfGenes
|
about 70-80
|
|
gptkbp:order
|
gptkb:Herpesvirales
|
|
gptkbp:primary_infection
|
gptkb:chickenpox
|
|
gptkbp:reactivation_causes
|
shingles
|
|
gptkbp:reactivation_risk_factors
|
aging
stress
immunosuppression
|
|
gptkbp:replicationSite
|
gptkb:nucleus
|
|
gptkbp:secondary_infection
|
shingles
|
|
gptkbp:size
|
approximately 150-200 nm
|
|
gptkbp:species
|
gptkb:Human_alphaherpesvirus_3
|
|
gptkbp:structure
|
icosahedral capsid
|
|
gptkbp:taxonRank
|
gptkb:Varicellovirus
|
|
gptkbp:transmissionRoute
|
direct contact
airborne droplets
|
|
gptkbp:vaccine_name
|
gptkb:Shingrix
gptkb:Varivax
gptkb:Zostavax
|
|
gptkbp:vaccineAvailable
|
true
|
|
gptkbp:WHOClassification
|
ICTV 2022: Human alphaherpesvirus 3
|
|
gptkbp:bfsParent
|
gptkb:Chickenpox
gptkb:Varicella
|
|
gptkbp:bfsLayer
|
5
|