myelin-associated glycoprotein

URI: https://gptkb.org/entity/myelin-associated_glycoprotein
GPTKB entity
Statements (29)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:Siglec-4
Sialic acid-binding Ig-like lectin 4
gptkbp:expressedIn gptkb:oligodendrocytes
Schwann cells
gptkbp:firstDescribed 1980s
gptkbp:foundIn central nervous system
peripheral nervous system
myelin sheath
gptkbp:function inhibits axonal regeneration
involved in myelin-axon interactions
gptkbp:gene gptkb:MAG
gptkbp:HGNC_ID 6807
https://www.w3.org/2000/01/rdf-schema#label myelin-associated glycoprotein
gptkbp:inhibitedBy neurite outgrowth
gptkbp:interactsWith axon surface molecules
gptkbp:locatedOnChromosome chromosome 19q13.1-q13.2
gptkbp:location gptkb:plasma_membrane
gptkbp:molecularWeight approximately 100 kDa
gptkbp:OMIM 159460
gptkbp:postTranslationalModification glycosylation
gptkbp:proteinFamily gptkb:immunoglobulin_superfamily
gptkbp:role gptkb:hereditary_spastic_paraplegia
multiple sclerosis
peripheral neuropathy
gptkbp:structure contains five immunoglobulin-like domains
gptkbp:UniProtID P20916
gptkbp:bfsParent gptkb:varicella-zoster_virus
gptkbp:bfsLayer 6