|
gptkbp:instanceOf
|
gptkb:chemical_compound
antiviral drug
|
|
gptkbp:approvalYear
|
1994
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
J05AB09
|
|
gptkbp:bioavailability
|
77%
|
|
gptkbp:brand
|
gptkb:Famvir
|
|
gptkbp:CASNumber
|
104227-87-4
|
|
gptkbp:chemicalFormula
|
C14H19N5O4
|
|
gptkbp:contraindication
|
hypersensitivity to famciclovir
hypersensitivity to penciclovir
|
|
gptkbp:developedBy
|
gptkb:SmithKline_Beecham
|
|
gptkbp:eliminationHalfLife
|
2-3 hours
|
|
gptkbp:excretion
|
renal
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
famciclovir
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
inhibits viral DNA polymerase
|
|
gptkbp:metabolism
|
gptkb:penciclovir
|
|
gptkbp:molecularWeight
|
321.33 g/mol
|
|
gptkbp:pregnancyCategory
|
B (US)
B1 (Australia)
|
|
gptkbp:prodrugOf
|
gptkb:penciclovir
|
|
gptkbp:PubChem_CID
|
60856
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
diarrhea
fatigue
headache
|
|
gptkbp:UNII
|
4Z2K6DNK39
|
|
gptkbp:usedFor
|
gptkb:herpes_simplex_virus
shingles
genital herpes
herpes zoster
cold sores
|
|
gptkbp:bfsParent
|
gptkb:Herpes_Simplex
gptkb:virus
|
|
gptkbp:bfsLayer
|
5
|