Statements (29)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:enzyme
|
gptkbp:alternativeName |
gptkb:tyrosine_transaminase
TAT |
gptkbp:biologicalProcess |
aminotransferase activity
tyrosine catabolic process |
gptkbp:CASNumber |
9030-37-9
|
gptkbp:catalyzes |
transamination of tyrosine to p-hydroxyphenylpyruvate
|
gptkbp:cofactor |
gptkb:pyridoxal_phosphate
|
gptkbp:deficiencyCauses |
gptkb:tyrosinemia_type_II
|
gptkbp:EC_number |
2.6.1.5
|
gptkbp:enzymeClassification |
transferase
|
gptkbp:foundIn |
gptkb:kidney
liver |
gptkbp:gene |
TAT
|
https://www.w3.org/2000/01/rdf-schema#label |
tyrosine aminotransferase
|
gptkbp:locatedOnChromosome |
16q22.1
|
gptkbp:OMIM |
276600
|
gptkbp:organism |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
gptkbp:pathway |
tyrosine metabolism
phenylalanine, tyrosine and tryptophan biosynthesis |
gptkbp:product |
gptkb:p-hydroxyphenylpyruvate
gptkb:L-glutamate |
gptkbp:structure |
homodimer
|
gptkbp:substrate |
gptkb:L-tyrosine
gptkb:2-oxoglutarate |
gptkbp:UniProtID |
P21549 (human)
|
gptkbp:bfsParent |
gptkb:pyridoxal_phosphate
|
gptkbp:bfsLayer |
7
|