Statements (71)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:physicist
|
| gptkbp:bfsLayer |
5
|
| gptkbp:bfsParent |
gptkb:Tyrolean_Airways
gptkb:Tyre_International_Airport gptkb:Blue_Seventy gptkb:Tyler_Pounds_Regional_Airport |
| gptkbp:associated_with |
albinism
|
| gptkbp:code |
tyrosinase
|
| gptkbp:discovered_by |
gptkb:Hermann_Joseph_Muller
|
| gptkbp:first_described_by |
1930s
|
| gptkbp:function |
catalyzes the conversion of tyrosine to DOPA
|
| gptkbp:genetic_diversity |
causes albinism
|
| gptkbp:has_role |
hair color determination
|
| gptkbp:has_variants |
SN Ps
|
| https://www.w3.org/2000/01/rdf-schema#label |
TYR
|
| gptkbp:interacts_with |
TYR P1
|
| gptkbp:is_aimed_at |
gptkb:physicist
|
| gptkbp:is_associated_with |
gptkb:psychologist
chronic diseases cardiovascular health neurodevelopmental disorders fertility issues skin disorders increased UV sensitivity melanoma risk |
| gptkbp:is_essential_for |
normal vision
|
| gptkbp:is_involved_in |
cell cycle regulation
cell differentiation cell proliferation cellular metabolism immune response neurotransmitter release stress response cell signaling pathways oxidative stress response cellular aging cellular signaling neurotransmitter synthesis cellular repair mechanisms neural crest development hormonal signaling cellular detoxification immune system regulation hormonal regulation of pigmentation melanin biosynthesis |
| gptkbp:is_linked_to |
gptkb:psychologist
metabolic disorders cognitive function metabolic syndrome chronic inflammation developmental disorders skin cancer risk endocrine function pigmentary disorders |
| gptkbp:is_part_of |
gptkb:physicist
gptkb:protein melanogenesis pathway |
| gptkbp:is_represented_in |
gptkb:embryonic_development
placenta lungs adipose tissue gastrointestinal tract hair follicles inner ear melanocytes retinal pigment epithelium |
| gptkbp:is_studied_in |
genetics research
|
| gptkbp:located_in |
human chromosome 11
|
| gptkbp:regulates |
micro RN As
|
| gptkbp:related_to |
skin pigmentation
|
| gptkbp:social_responsibility |
gptkb:Oculocutaneous_albinism_type_1
|