tumor necrosis factor alpha-induced protein 3

GPTKB entity

Statements (22)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:A20
gptkbp:associatedWith leukemia
autoimmune diseases
inflammatory diseases
gptkbp:discoveredBy 1990s
gptkbp:expressedIn various tissues
gptkbp:function negative regulator of NF-kappaB signaling
ubiquitin-editing enzyme
gptkbp:gene gptkb:TNFAIP3
https://www.w3.org/2000/01/rdf-schema#label tumor necrosis factor alpha-induced protein 3
gptkbp:inhibitedBy NF-kappaB activation
TNF-induced apoptosis
gptkbp:locatedOnChromosome gptkb:6q23
gptkbp:molecularWeight 90 kDa
gptkbp:organism gptkb:Homo_sapiens
gptkbp:regulates inflammation
immune response
cell death
gptkbp:UniProtID P21580
gptkbp:bfsParent gptkb:A20_protein
gptkbp:bfsLayer 7