tryptophan 2,3-dioxygenase enzyme

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:enzyme
gptkbp:alternativeName gptkb:tryptophan_pyrrolase
gptkb:TDO
gptkbp:biologicalProcess oxidoreductase activity
gptkbp:catalyzes oxidation of L-tryptophan to N-formylkynurenine
gptkbp:cellularComponent cytosol
gptkbp:cofactor hemoglobin
gptkbp:EC_number 1.13.11.11
gptkbp:foundIn liver
gptkbp:gene gptkb:TDO2
gptkbp:GO_term GO:0004833
https://www.w3.org/2000/01/rdf-schema#label tryptophan 2,3-dioxygenase enzyme
gptkbp:organism gptkb:Mus_musculus
gptkb:Homo_sapiens
gptkbp:pathway tryptophan catabolism
gptkbp:product N-formylkynurenine
gptkbp:regulates induced by glucocorticoids
inhibited by tryptophan analogs
gptkbp:requires molecular oxygen
gptkbp:substrate L-tryptophan
gptkbp:UniProtID P48775 (human)
gptkbp:bfsParent gptkb:TDO2
gptkbp:bfsLayer 7