Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:receptor_tyrosine_kinase
gptkb:G_protein-coupled_receptor |
| gptkbp:alternativeName |
HTR1D
5-hydroxytryptamine receptor 1D |
| gptkbp:couplingType |
Gi/Go protein
|
| gptkbp:encodedBy |
HTR1D gene
|
| gptkbp:enemyOf |
gptkb:rizatriptan
gptkb:zolmitriptan sumatriptan GR127935 SB-216641 |
| gptkbp:Entrez_Gene_ID |
3352
|
| gptkbp:expressedIn |
brain
cerebral blood vessels |
| gptkbp:foundIn |
gptkb:human
mammals |
| gptkbp:function |
modulates neurotransmitter release
inhibits adenylate cyclase |
| https://www.w3.org/2000/01/rdf-schema#label |
5-HT1D receptor
|
| gptkbp:ligand |
serotonin
|
| gptkbp:locatedOnChromosome |
1p36.3-p34.3
|
| gptkbp:modulatedBy |
vasoconstriction
|
| gptkbp:OMIM |
182131
|
| gptkbp:relatedTo |
migraine
|
| gptkbp:structureType |
7-transmembrane domain protein
|
| gptkbp:UniProtID |
P28221
|
| gptkbp:bfsParent |
gptkb:triptans
gptkb:5-HT1_receptor |
| gptkbp:bfsLayer |
7
|