|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:prealbumin
|
|
gptkbp:associatedWith
|
gptkb:familial_amyloid_cardiomyopathy
gptkb:familial_amyloid_polyneuropathy
gptkb:senile_systemic_amyloidosis
|
|
gptkbp:binds
|
thyroxine
retinol-binding protein
|
|
gptkbp:degradedBy
|
gptkb:proteasome
|
|
gptkbp:discoveredBy
|
gptkb:Richard_J._Robbins
|
|
gptkbp:encodedBy
|
gptkb:TTR_gene
|
|
gptkbp:firstDescribed
|
1942
|
|
gptkbp:foundIn
|
retina
liver
choroid plexus
|
|
gptkbp:function
|
transports retinol (vitamin A)
transports thyroxine (T4)
|
|
gptkbp:halfLife
|
2 days
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
transthyretin protein
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_18q12.1
|
|
gptkbp:medicalUse
|
marker of nutritional status
|
|
gptkbp:molecularWeight
|
approximately 55 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:Val30Met
Thr60Ala
Val122Ile
|
|
gptkbp:OMIM
|
176300
|
|
gptkbp:PDB
|
gptkb:1F41
|
|
gptkbp:presentIn
|
gptkb:plasma
eye
cerebrospinal fluid
|
|
gptkbp:structure
|
tetramer
|
|
gptkbp:UniProtID
|
gptkb:P02766
|
|
gptkbp:bfsParent
|
gptkb:TTR_gene
gptkb:hereditary_transthyretin_amyloidosis
gptkb:acoramidis
|
|
gptkbp:bfsLayer
|
7
|