Statements (36)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:disease
amyloidosis |
| gptkbp:affects |
gptkb:carpal_tunnel
heart kidneys elderly individuals |
| gptkbp:alsoKnownAs |
gptkb:wild-type_transthyretin_amyloidosis
|
| gptkbp:causedBy |
deposition of wild-type transthyretin protein
|
| gptkbp:complication |
gptkb:arrhythmias
heart failure restrictive cardiomyopathy |
| gptkbp:diagnosedBy |
biopsy
echocardiogram cardiac MRI scintigraphy |
| gptkbp:firstDescribed |
1930s
|
| https://www.w3.org/2000/01/rdf-schema#label |
senile systemic amyloidosis
|
| gptkbp:ICD-10_code |
E85.4
|
| gptkbp:MeSH_ID |
D000686
|
| gptkbp:OMIM |
105210
|
| gptkbp:prevalence |
increases with age
|
| gptkbp:prognosis |
progressive
|
| gptkbp:riskFactor |
male sex
advanced age |
| gptkbp:symptom |
gptkb:arrhythmia
congestive heart failure fatigue dyspnea |
| gptkbp:treatment |
gptkb:tafamidis
supportive care diuretics heart failure medications |
| gptkbp:bfsParent |
gptkb:TTR_gene
gptkb:wild-type_transthyretin_amyloidosis gptkb:transthyretin |
| gptkbp:bfsLayer |
7
|