|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:TBPA
gptkb:Prealbumin
|
|
gptkbp:associatedWith
|
gptkb:Familial_amyloid_cardiomyopathy
gptkb:Familial_amyloid_polyneuropathy
gptkb:Senile_systemic_amyloidosis
|
|
gptkbp:biologicalProcess
|
retinoid transport
retinol binding
thyroid hormone transport
thyroxine binding
|
|
gptkbp:chain
|
21-147
|
|
gptkbp:clinical_variant
|
gptkb:Val30Met
Thr119Met
|
|
gptkbp:disulfideBond
|
Cys10-Cys22
|
|
gptkbp:EC_number
|
nan
|
|
gptkbp:Entrez_Gene_ID
|
ENSP00000330707
|
|
gptkbp:expressedIn
|
high in liver
high in choroid plexus
|
|
gptkbp:function
|
Transports thyroxine and retinol-binding protein-bound retinol
|
|
gptkbp:gene
|
gptkb:TTR
|
|
gptkbp:hasIsoform
|
2
|
|
gptkbp:HGNC_ID
|
gptkb:HGNC:12405
|
|
gptkbp:InterPro
|
IPR001534
|
|
gptkbp:KEGGID
|
hsa:7276
|
|
gptkbp:locatedOnChromosome
|
18
|
|
gptkbp:molecularWeight
|
15986 Da
|
|
gptkbp:OMIM
|
176300
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:PDB
|
gptkb:1F41
1ICT
1TTA
|
|
gptkbp:postTranslationalModification
|
Disulfide bond
Glycosylation
|
|
gptkbp:protein_name
|
gptkb:Transthyretin
|
|
gptkbp:proteinFamily
|
PF01060
|
|
gptkbp:Reactome
|
R-HSA-381340
|
|
gptkbp:RefSeq
|
NP_000362.1
|
|
gptkbp:sequence
|
147
|
|
gptkbp:sequenceStatus
|
complete
|
|
gptkbp:signalPeptide
|
1-20
|
|
gptkbp:subcellularLocation
|
gptkb:Cerebrospinal_fluid
Plasma
Secreted
|
|
gptkbp:subunit
|
Homotetramer
|
|
gptkbp:tissue_specificity
|
gptkb:Choroid_plexus
Liver
|
|
gptkbp:UniGene
|
Hs.654
|
|
gptkbp:UniProtID
|
gptkb:P02766
|
|
gptkbp:bfsParent
|
gptkb:TTR_gene
|
|
gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
P02766
|