transmembrane protein 106B

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:alternativeName	gptkb:TMEM106B transmembrane protein 106B isoform 1
gptkbp:associatedWith	neurodegenerative diseases frontotemporal lobar degeneration
gptkbp:Entrez_Gene_ID	91972
gptkbp:expressedIn	gptkb:cancer gptkb:kidney brain liver
gptkbp:foundIn	gptkb:Homo_sapiens
gptkbp:function	protein trafficking lysosomal function regulation
gptkbp:gene	gptkb:TMEM106B TMEM106B gene
gptkbp:involves	autophagy lysosomal homeostasis
gptkbp:length	274
gptkbp:locatedIn	lysosomal membrane
gptkbp:locatedOnChromosome	chromosome 7p21
gptkbp:mutationAssociatedWith	frontotemporal dementia
gptkbp:OMIM	613413
gptkbp:orthologInMouse	Tmem106b
gptkbp:predicted_isoelectric_point	pI 8.6
gptkbp:predicted_molecular_weight	31 kDa
gptkbp:structure	single-pass type II membrane protein
gptkbp:subcellularLocation	gptkb:lysosome gptkb:endosome
gptkbp:UniProtID	Q9NUM4
gptkbp:bfsParent	gptkb:HGNC:26144 gptkb:HGNC:30257 gptkb:HGNC:29022 gptkb:Q8N6M6 gptkb:TMEM106B
gptkbp:bfsLayer	8
https://www.w3.org/2000/01/rdf-schema#label	transmembrane protein 106B