transmembrane protein 106B

URI: https://gptkb.org/entity/transmembrane_protein_106B
GPTKB entity
Statements (32)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alternativeName gptkb:TMEM106B
transmembrane protein 106B isoform 1
gptkbp:associatedWith neurodegenerative diseases
frontotemporal lobar degeneration
gptkbp:Entrez_Gene_ID 91972
gptkbp:expressedIn gptkb:cancer
gptkb:kidney
brain
liver
gptkbp:foundIn gptkb:Homo_sapiens
gptkbp:function protein trafficking
lysosomal function regulation
gptkbp:gene gptkb:TMEM106B
TMEM106B gene
https://www.w3.org/2000/01/rdf-schema#label transmembrane protein 106B
gptkbp:involves autophagy
lysosomal homeostasis
gptkbp:length 274
gptkbp:locatedIn lysosomal membrane
gptkbp:locatedOnChromosome chromosome 7p21
gptkbp:mutationAssociatedWith frontotemporal dementia
gptkbp:OMIM 613413
gptkbp:orthologInMouse Tmem106b
gptkbp:predicted_isoelectric_point pI 8.6
gptkbp:predicted_molecular_weight 31 kDa
gptkbp:structure single-pass type II membrane protein
gptkbp:subcellularLocation gptkb:lysosome
gptkb:endosome
gptkbp:UniProtID Q9NUM4
gptkbp:bfsParent gptkb:HGNC:26144
gptkbp:bfsLayer 7