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gptkbp:instanceOf
|
gptkb:protein
|
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gptkbp:abbreviation
|
gptkb:CRP
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gptkbp:alternativeName
|
gptkb:pentraxin_1
|
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gptkbp:category
|
clinical chemistry
immunology
biomarker
acute-phase reactant
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gptkbp:decreasedIn
|
resolution of inflammation
|
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gptkbp:discoveredBy
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gptkb:Tillett_and_Francis
|
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gptkbp:discoveredIn
|
1930
|
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gptkbp:elevatedIn
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gptkb:systemic_lupus_erythematosus
gptkb:Bacteria
myocardial infarction
inflammatory diseases
rheumatoid arthritis
tissue injury
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gptkbp:encodedBy
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gptkb:CRP_gene
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gptkbp:Entrez_Gene_ID
|
1401
|
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gptkbp:foundIn
|
blood plasma
|
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gptkbp:function
|
activates complement system
acute-phase protein
binds to phosphocholine
marker of inflammation
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gptkbp:halfLife
|
~19 hours
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
C-reactive protein
|
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gptkbp:improves
|
gptkb:interleukin-6
inflammation
|
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gptkbp:locatedOnChromosome
|
1q23.2
|
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gptkbp:measures
|
blood test
|
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gptkbp:medicalUse
|
diagnosis of infection
diagnosis of inflammation
monitoring of autoimmune diseases
risk assessment for cardiovascular disease
|
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gptkbp:MeSH_ID
|
gptkb:D003371
|
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gptkbp:molecularWeight
|
~115 kDa
|
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gptkbp:OMIM
|
123260
|
|
gptkbp:PDB
|
gptkb:1B09
|
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gptkbp:producedBy
|
liver
|
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gptkbp:range
|
<10 mg/L (normal)
|
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gptkbp:relatedTo
|
gptkb:high-sensitivity_CRP_(hs-CRP)
gptkb:serum_amyloid_P_component
|
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gptkbp:structure
|
pentameric
|
|
gptkbp:subunit
|
5 identical subunits
|
|
gptkbp:UniProtID
|
gptkb:P02741
|
|
gptkbp:usedIn
|
cardiovascular risk assessment
high-sensitivity CRP test
infection monitoring
inflammatory disease monitoring
|
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gptkbp:bfsParent
|
gptkb:CR
|
|
gptkbp:bfsLayer
|
5
|