|
gptkbp:instance_of
|
gptkb:Bastiladon
|
|
gptkbp:administered_by
|
oral tablet
injectable solution
|
|
gptkbp:approves
|
gptkb:FDA
|
|
gptkbp:brand
|
gptkb:Silvadene
Thermazene
|
|
gptkbp:casnumber
|
68-35-9
|
|
gptkbp:chemical_formula
|
C10 H10 N4 O2 S
|
|
gptkbp:class
|
gptkb:Bastiladon
|
|
gptkbp:clinical_trial
|
Phase IV
Phase II
Phase III
Phase I
|
|
gptkbp:composed_by
|
gptkb:chemical_compound
reaction of sulfanilamide with diazine
|
|
gptkbp:contraindication
|
pregnancy
hypersensitivity to sulfonamides
|
|
gptkbp:developed_by
|
gptkb:Glaxo_Smith_Kline
|
|
gptkbp:dosage_form
|
gptkb:cream
ointment
|
|
gptkbp:excretion
|
urine
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
sulfadiazine
|
|
gptkbp:indication
|
gptkb:pneumocystis_pneumonia
gptkb:Burning_Man
meningitis
urinary tract infections
|
|
gptkbp:interacts_with
|
gptkb:methotrexate
gptkb:phenytoin
gptkb:warfarin
|
|
gptkbp:lifespan
|
6 to 12 hours
|
|
gptkbp:mechanism_of_action
|
inhibits bacterial folic acid synthesis
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:related_to
|
gptkb:sulfamethoxazole
gptkb:sulfanilamide
|
|
gptkbp:research_areas
|
pharmacokinetics
antimicrobial resistance
drug interactions
clinical efficacy
|
|
gptkbp:route_of_administration
|
oral
intravenous
topical
|
|
gptkbp:safety
|
Category C
|
|
gptkbp:shelf_life
|
3 years
|
|
gptkbp:side_effect
|
nausea
fever
vomiting
rash
|
|
gptkbp:storage
|
room temperature
protected from light
|
|
gptkbp:used_for
|
treatment of bacterial infections
treatment of toxoplasmosis
|
|
gptkbp:bfsParent
|
gptkb:sulfanilamide
|
|
gptkbp:bfsLayer
|
7
|