Statements (36)
Predicate | Object |
---|---|
gptkbp:instanceOf |
molecular complex
|
gptkbp:alternativeName |
RNA spliceosome
|
gptkbp:assembly |
stepwise
|
gptkbp:component |
gptkb:U2_snRNP
U1 snRNP U4 snRNP U5 snRNP U6 snRNP protein factors snRNP |
gptkbp:contains |
proteins
non-coding RNA |
gptkbp:discoveredIn |
1970s
|
gptkbp:dysregulationAssociatedWith |
gptkb:cancer
gptkb:disease spinal muscular atrophy |
gptkbp:evolvesFrom |
eukaryotes
|
gptkbp:foundIn |
eukaryotes
|
gptkbp:function |
removal of introns from pre-mRNA
|
https://www.w3.org/2000/01/rdf-schema#label |
spliceosome
|
gptkbp:location |
gptkb:nucleus
|
gptkbp:PDB |
yes
|
gptkbp:processor |
splicing
|
gptkbp:regulates |
alternative splicing
|
gptkbp:relatedTo |
gene expression
pre-mRNA mRNA maturation |
gptkbp:requires |
gptkb:ATP
|
gptkbp:size |
large
|
gptkbp:structure |
dynamic
|
gptkbp:studiedBy |
geneticists
biochemists molecular biologists |
gptkbp:studiedIn |
molecular biology
|
gptkbp:bfsParent |
gptkb:non-coding_RNA
|
gptkbp:bfsLayer |
6
|