spliceosome

GPTKB entity

Statements (36)
Predicate Object
gptkbp:instanceOf molecular complex
gptkbp:alternativeName RNA spliceosome
gptkbp:assembly stepwise
gptkbp:component gptkb:U2_snRNP
U1 snRNP
U4 snRNP
U5 snRNP
U6 snRNP
protein factors
snRNP
gptkbp:contains proteins
non-coding RNA
gptkbp:discoveredIn 1970s
gptkbp:dysregulationAssociatedWith gptkb:cancer
gptkb:disease
spinal muscular atrophy
gptkbp:evolvesFrom eukaryotes
gptkbp:foundIn eukaryotes
gptkbp:function removal of introns from pre-mRNA
https://www.w3.org/2000/01/rdf-schema#label spliceosome
gptkbp:location gptkb:nucleus
gptkbp:PDB yes
gptkbp:processor splicing
gptkbp:regulates alternative splicing
gptkbp:relatedTo gene expression
pre-mRNA
mRNA maturation
gptkbp:requires gptkb:ATP
gptkbp:size large
gptkbp:structure dynamic
gptkbp:studiedBy geneticists
biochemists
molecular biologists
gptkbp:studiedIn molecular biology
gptkbp:bfsParent gptkb:non-coding_RNA
gptkbp:bfsLayer 6