Statements (73)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:protein
|
| gptkbp:associated_with |
gptkb:muscular_dystrophy
|
| gptkbp:composed_of |
survival motor neuron protein
|
| gptkbp:contains |
gptkb:SMN1_gene
gptkb:SMN2_gene |
| gptkbp:discovered_by |
gptkb:humans
|
| gptkbp:function |
involved in the assembly of spliceosomal sn RNPs
|
| gptkbp:has_role |
cellular stress response
RNA processing |
| https://www.w3.org/2000/01/rdf-schema#label |
SMN complex
|
| gptkbp:interacts_with |
Gemins
|
| gptkbp:involved_in |
gene expression regulation
|
| gptkbp:is_associated_with |
aging
immune response cognitive function muscle atrophy cellular signaling pathways neurodegeneration synaptic function neurotransmitter synthesis cellular repair mechanisms cellular apoptosis Gem bodies |
| gptkbp:is_characterized_by |
highly conserved regions
|
| gptkbp:is_disrupted_in |
certain cancers
|
| gptkbp:is_essential_for |
motor neuron survival
sn RNP biogenesis |
| gptkbp:is_expressed_in |
various tissues
|
| gptkbp:is_found_in |
gptkb:Brain
|
| gptkbp:is_involved_in |
DNA repair
cell cycle regulation cell differentiation cellular homeostasis cellular metabolism neurotransmitter release protein synthesis neuroinflammation cellular differentiation protein folding neuroprotection cellular signaling pathways cellular communication cellular signaling nuclear transport cellular growth mechanisms cellular differentiation processes cellular repair stress granule formation neurotransmitter signaling m RNA splicing cellular stress response mechanisms |
| gptkbp:is_linked_to |
apoptosis
cellular metabolism metabolic processes synaptic plasticity developmental disorders neurodevelopmental processes cellular communication pathways cellular growth cellular stress response pathways axon growth autosomal recessive disorders |
| gptkbp:is_part_of |
gptkb:spliceosome
RNA metabolism |
| gptkbp:is_regulated_by |
phosphorylation
|
| gptkbp:is_studied_in |
biomedical research
|
| gptkbp:is_targeted_at |
therapeutic agents
|
| gptkbp:located_in |
gptkb:Atom
|
| gptkbp:related_to |
gptkb:neurodegenerative_diseases
|
| gptkbp:bfsParent |
gptkb:SMN2
gptkb:SMN1_gene gptkb:SMN2_gene |
| gptkbp:bfsLayer |
6
|