Statements (27)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:LR11
gptkb:SORLA |
| gptkbp:associatedWith |
gptkb:Alzheimer's_disease
|
| gptkbp:Entrez_Gene_ID |
ENSG00000137642
|
| gptkbp:expressedIn |
gptkb:kidney
brain liver |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
regulation of endocytosis
trafficking of amyloid precursor protein |
| gptkbp:gene |
gptkb:SORL1
|
| gptkbp:geneType |
protein-coding
|
| gptkbp:HGNC_ID |
HGNC:11185
|
| https://www.w3.org/2000/01/rdf-schema#label |
sortilin-related receptor 1
|
| gptkbp:interactsWith |
gptkb:apolipoprotein_E
gptkb:amyloid_precursor_protein |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_11q24.1
|
| gptkbp:location |
gptkb:endosome
gptkb:cell_membrane |
| gptkbp:molecularWeight |
~250 kDa
|
| gptkbp:mutationAssociatedWith |
increased risk of Alzheimer's disease
|
| gptkbp:OMIM |
602005
|
| gptkbp:proteinFamily |
VPS10 domain receptors
|
| gptkbp:UniProtID |
Q92673
|
| gptkbp:bfsParent |
gptkb:SORL1
|
| gptkbp:bfsLayer |
8
|