Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
HSP20 family
alpha-crystallin-related proteins |
| gptkbp:associatedWith |
gptkb:cancer
gptkb:cataracts neurodegenerative diseases |
| gptkbp:conservedFeature |
alpha-crystallin domain
|
| gptkbp:domain |
alpha-crystallin domain
|
| gptkbp:example |
gptkb:HSP27
alphaB-crystallin HSP20 |
| gptkbp:foundIn |
gptkb:Bacteria
animals fungi plants |
| gptkbp:fullName |
small heat shock proteins
|
| gptkbp:function |
molecular chaperone
prevention of protein aggregation |
| https://www.w3.org/2000/01/rdf-schema#label |
small HSPs
|
| gptkbp:inducedBy |
oxidative stress
heat shock other cellular stresses |
| gptkbp:locale |
gptkb:nucleus
gptkb:cytoplasm mitochondria chloroplasts (in plants) |
| gptkbp:molecularWeight |
12-43 kDa
|
| gptkbp:oligomerization |
form large oligomeric complexes
|
| gptkbp:proteinFamily |
HSPB
|
| gptkbp:regulates |
transcriptional upregulation under stress
|
| gptkbp:role |
cellular stress response
protein homeostasis protection against apoptosis |
| gptkbp:bfsParent |
gptkb:HSP_gene_family
|
| gptkbp:bfsLayer |
6
|