|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
HSP20 family
alpha-crystallin-related proteins
|
|
gptkbp:associatedWith
|
gptkb:cancer
gptkb:cataracts
neurodegenerative diseases
|
|
gptkbp:conservedFeature
|
alpha-crystallin domain
|
|
gptkbp:domain
|
alpha-crystallin domain
|
|
gptkbp:example
|
gptkb:HSP27
alphaB-crystallin
HSP20
|
|
gptkbp:foundIn
|
gptkb:Bacteria
animals
fungi
plants
|
|
gptkbp:fullName
|
small heat shock proteins
|
|
gptkbp:function
|
gptkb:molecular_chaperone
prevention of protein aggregation
|
|
gptkbp:inducedBy
|
oxidative stress
heat shock
other cellular stresses
|
|
gptkbp:locale
|
gptkb:nucleus
gptkb:cytoplasm
mitochondria
chloroplasts (in plants)
|
|
gptkbp:molecularWeight
|
12-43 kDa
|
|
gptkbp:oligomerization
|
form large oligomeric complexes
|
|
gptkbp:proteinFamily
|
HSPB
|
|
gptkbp:regulates
|
transcriptional upregulation under stress
|
|
gptkbp:role
|
gptkb:cellular_stress_response
protein homeostasis
protection against apoptosis
|
|
gptkbp:bfsParent
|
gptkb:HSP_gene_family
|
|
gptkbp:bfsLayer
|
7
|
|
http://www.w3.org/2000/01/rdf-schema#label
|
small HSPs
|