|
gptkbp:instance_of
|
gptkb:software
|
|
gptkbp:bfsLayer
|
4
|
|
gptkbp:bfsParent
|
gptkb:Nexavar
|
|
gptkbp:activities
|
HMG-Co A reductase inhibitor
|
|
gptkbp:approves
|
gptkb:1991
gptkb:FDA
|
|
gptkbp:brand
|
Zocor
|
|
gptkbp:clinical_trial
|
Phase IV
Phase III
|
|
gptkbp:contraindication
|
pregnancy
breastfeeding
active liver disease
|
|
gptkbp:dosage_form
|
10 mg
oral tablet
5 mg
20 mg
80 mg
40 mg
5 to 40 mg daily
|
|
gptkbp:formulation
|
gptkb:tablet
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
simvastatin
|
|
gptkbp:ingredients
|
C25 H38 O5
|
|
gptkbp:interacts_with
|
gptkb:beer
gptkb:HIV_protease_inhibitors
certain antibiotics
antifungal medications
other statins
|
|
gptkbp:invention
|
gptkb:2006
|
|
gptkbp:is_atype_of
|
C10 A A01
|
|
gptkbp:is_used_for
|
hyperlipidemia
cardiovascular disease prevention
|
|
gptkbp:marketed_as
|
gptkb:legislation
gptkb:Australia
gptkb:Japan
gptkb:United_States
gptkb:Native_American_tribe
|
|
gptkbp:previous_name
|
gptkb:battle
|
|
gptkbp:produced_by
|
gptkb:Merck_&_Co.
|
|
gptkbp:related_to
|
gptkb:rosuvastatin
gptkb:atorvastatin
fluvastatin
lovastatin
pravastatin
|
|
gptkbp:side_effect
|
muscle pain
allergic reactions
liver damage
kidney failure
cognitive impairment
pancreatitis
digestive problems
rhabdomyolysis
increased blood sugar
|
|
gptkbp:storage
|
room temperature
protected from light
protected from moisture
|