serotonin 5-HT2A receptor

URI: https://gptkb.org/entity/serotonin_5-HT2A_receptor
GPTKB entity
Statements (46)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkb:G_protein-coupled_receptor
gptkbp:alternativeName 5-HT2A receptor
5-hydroxytryptamine receptor 2A
gptkbp:binds antipsychotic drugs
psychedelic drugs
serotonin
gptkbp:discoveredBy gptkb:David_Julius
gptkbp:discoveredIn 1988
gptkbp:encodedBy HTR2A gene
gptkbp:enemyOf gptkb:psilocin
gptkb:clozapine
gptkb:olanzapine
gptkb:risperidone
gptkb:cyproheptadine
LSD
mescaline
mirtazapine
ketanserin
gptkbp:foundIn gptkb:cerebral_cortex
central nervous system
platelets
gptkbp:function regulates mood
mediates excitatory neurotransmission
regulates cognition
regulates perception
https://www.w3.org/2000/01/rdf-schema#label serotonin 5-HT2A receptor
gptkbp:locatedOnChromosome chromosome 13q14-q21 (human)
gptkbp:OMIM 182135
gptkbp:relatedTo gptkb:depression
memory
schizophrenia
learning
anxiety
hallucinations
migraine
sleep regulation
gptkbp:structure seven transmembrane domains
gptkbp:type Gq/11 protein pathway
gptkbp:UniProtID P28223
gptkbp:bfsParent gptkb:CHEMBL2364609
gptkb:CHEMBL2104746
gptkb:CHEMBL2105721
gptkb:Clozaril
gptkb:CHEMBL2105727
gptkbp:bfsLayer 7