Statements (34)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
antineoplastic agent histone deacetylase inhibitor |
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
gptkb:L01XX43
|
| gptkbp:brand |
Istodax
|
| gptkbp:CASNumber |
128517-07-7
|
| gptkbp:discoveredBy |
gptkb:Fujisawa_Pharmaceutical
|
| gptkbp:hasMolecularFormula |
C24H36N4O6S2
|
| gptkbp:hasSMILES |
CC1CC(C2C(=O)NC(C(=O)N2C1=O)CSC3=CC=CC=C3)NC(=O)C4CC(C(=O)N4)NC(=O)C
|
| https://www.w3.org/2000/01/rdf-schema#label |
romidepsin
|
| gptkbp:KEGGID |
D08913
|
| gptkbp:legalStatus |
prescription only
|
| gptkbp:mechanismOfAction |
inhibits histone deacetylase
|
| gptkbp:molecularWeight |
540.7 g/mol
|
| gptkbp:origin |
Chromobacterium violaceum
|
| gptkbp:PubChem_CID |
CHEMBL1201836
4508416 5352062 DB06186 |
| gptkbp:routeOfAdministration |
intravenous
|
| gptkbp:sideEffect |
gptkb:anemia
nausea vomiting fatigue infections thrombocytopenia |
| gptkbp:synonym |
FK228
depsipeptide |
| gptkbp:UNII |
Q1K0A10YF7
|
| gptkbp:usedFor |
leukemia
peripheral T-cell lymphoma |
| gptkbp:bfsParent |
gptkb:Histone_deacetylase
|
| gptkbp:bfsLayer |
7
|