Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alias |
gptkb:AD3L
gptkb:STM2 gptkb:PS2 |
| gptkbp:alternativeSplicing |
produces multiple transcript variants
|
| gptkbp:associatedWith |
gptkb:Alzheimer's_disease
|
| gptkbp:cellularComponent |
gptkb:Golgi_apparatus_membrane
gptkb:nuclear_membrane endoplasmic reticulum membrane |
| gptkbp:encodedBy |
gptkb:PSEN2_gene
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
component of gamma-secretase complex
|
| https://www.w3.org/2000/01/rdf-schema#label |
presenilin-2
|
| gptkbp:involvedIn |
Notch receptor processing
proteolytic processing of amyloid precursor protein |
| gptkbp:length |
448 amino acids
|
| gptkbp:location |
gptkb:chromosome_1q42.13
|
| gptkbp:MIM_number |
gptkb:600759
|
| gptkbp:molecularWeight |
50 kDa
|
| gptkbp:mutationAssociatedWith |
can cause familial Alzheimer's disease
|
| gptkbp:orthologIn |
gptkb:presenilin-1
|
| gptkbp:UniProtID |
gptkb:P49810
|
| gptkbp:bfsParent |
gptkb:Alzheimer's_disease_pathway
|
| gptkbp:bfsLayer |
7
|