Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:abbreviation |
gptkb:PDE9
|
| gptkbp:encodedBy |
PDE9A gene
|
| gptkbp:enzymeClassification |
EC 3.1.4.54
|
| gptkbp:expressedIn |
gptkb:cancer
gptkb:kidney brain heart liver |
| gptkbp:foundIn |
gptkb:human
mammals |
| gptkbp:function |
hydrolyzes cGMP
|
| https://www.w3.org/2000/01/rdf-schema#label |
phosphodiesterase type 9
|
| gptkbp:inhibitedBy |
BAY 73-6691
PF-04447943 |
| gptkbp:locatedOnChromosome |
chromosome 21q22.3
|
| gptkbp:potentialDrugTargetFor |
gptkb:Alzheimer's_disease
cognitive disorders |
| gptkbp:role |
cGMP signaling pathway
|
| gptkbp:substrate |
gptkb:cGMP
|
| gptkbp:UniProtID |
O76083
|
| gptkbp:bfsParent |
gptkb:Phosphodiesterase
|
| gptkbp:bfsLayer |
7
|