Statements (22)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:enzyme
|
| gptkbp:biologicalProcess |
signal transduction
3',5'-cyclic-AMP phosphodiesterase activity cAMP catabolic process |
| gptkbp:catalyzes |
hydrolysis of cAMP
|
| gptkbp:encodedBy |
PDE8A gene
PDE8B gene |
| gptkbp:enzymeCommissionNumber |
3.1.4.17
|
| gptkbp:foundIn |
gptkb:Mus_musculus
gptkb:Homo_sapiens |
| gptkbp:function |
regulation of intracellular cAMP levels
|
| gptkbp:hasIsoform |
PDE8A
PDE8B |
| https://www.w3.org/2000/01/rdf-schema#label |
phosphodiesterase type 8
|
| gptkbp:inhibitedBy |
dipyridamole
PF-04957325 |
| gptkbp:location |
gptkb:nucleus
gptkb:cytoplasm |
| gptkbp:proteinFamily |
gptkb:PDE8
|
| gptkbp:substrate |
gptkb:cAMP
|
| gptkbp:bfsParent |
gptkb:Phosphodiesterase
|
| gptkbp:bfsLayer |
7
|