Afinitor

URI: https://gptkb.org/entity/Afinitor

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:drug
gptkbp:approvedBy	gptkb:FDA gptkb:EMA 2009
gptkbp:associatedWith	gptkb:sirolimus gptkb:temsirolimus
gptkbp:ATCCode	L01EG02
gptkbp:brand	gptkb:everolimus
gptkbp:CASNumber	gptkb:159351-69-6
gptkbp:chemicalFormula	C53H83NO14
gptkbp:contraindication	hypersensitivity to everolimus
gptkbp:indication	gptkb:advanced_hormone_receptor-positive,_HER2-negative_breast_cancer gptkb:advanced_renal_cell_carcinoma tuberous sclerosis complex-associated renal angiomyolipoma progressive neuroendocrine tumors of pancreatic origin tuberous sclerosis complex-associated subependymal giant cell astrocytoma
gptkbp:legalStatus	prescription only
gptkbp:manufacturer	gptkb:Novartis
gptkbp:mechanismOfAction	gptkb:mTOR_inhibitor
gptkbp:pregnancyCategory	D (US)
gptkbp:routeOfAdministration	oral
gptkbp:sideEffect	diarrhea fatigue infections rash stomatitis
gptkbp:usedFor	gptkb:tuberous_sclerosis_complex gptkb:cancer gptkb:renal_cell_carcinoma gptkb:pancreatic_neuroendocrine_tumors gptkb:subependymal_giant_cell_astrocytoma
gptkbp:bfsParent	gptkb:Novartis
gptkbp:bfsLayer	6
https://www.w3.org/2000/01/rdf-schema#label	Afinitor