|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:associatedWith
|
gptkb:medulloblastoma
gptkb:Waardenburg_syndrome
gptkb:aniridia
congenital hypothyroidism
Alveolar rhabdomyosarcoma
renal-coloboma syndrome
|
|
gptkbp:conservedIn
|
paired box domain
|
|
gptkbp:discoveredBy
|
gptkb:Peter_Gruss
|
|
gptkbp:domain
|
paired box domain
|
|
gptkbp:encodes
|
transcription factors
|
|
gptkbp:expressedIn
|
gptkb:thyroid
gptkb:olfactory_system
gptkb:skeletal_muscle
gptkb:nervous_system
gptkb:kidney
gptkb:spinal_cord
eye
pancreas
ear
craniofacial structures
limb buds
parathyroid
|
|
gptkbp:firstDescribed
|
1980s
|
|
gptkbp:foundIn
|
animals
|
|
gptkbp:hasParalogs
|
PAX1-PAX9
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
paired box (PAX) genes
|
|
gptkbp:includes
|
gptkb:PAX2
gptkb:PAX5
gptkb:PAX3
gptkb:PAX7
gptkb:PAX8
gptkb:PAX1
gptkb:PAX4
gptkb:PAX6
gptkb:PAX9
|
|
gptkbp:involvedIn
|
cell differentiation
embryonic development
|
|
gptkbp:locatedOn
|
various human chromosomes
|
|
gptkbp:mutationAssociatedWith
|
gptkb:cancer
developmental disorders
|
|
gptkbp:namedAfter
|
Drosophila gene 'paired'
|
|
gptkbp:numberOfGenes
|
9
|
|
gptkbp:orthologIn
|
invertebrates
vertebrates
|
|
gptkbp:regulates
|
apoptosis
proliferation
cell fate determination
organogenesis
tissue patterning
|
|
gptkbp:bfsParent
|
gptkb:Pax_gene_family
|
|
gptkbp:bfsLayer
|
8
|