|
gptkbp:instanceOf
|
cytokine
|
|
gptkbp:actsOn
|
gptkb:hepatocytes
endothelial cells
fibroblasts
|
|
gptkbp:alias
|
gptkb:OSM
|
|
gptkbp:discoveredIn
|
1986
|
|
gptkbp:effect
|
induces differentiation in some cell types
inhibits proliferation of some tumor cell lines
stimulates production of acute phase proteins
|
|
gptkbp:encodedBy
|
OSM gene
|
|
gptkbp:Entrez_Gene_ID
|
5008
|
|
gptkbp:foundIn
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:function
|
regulation of inflammation
modulation of cell growth
induction of acute phase proteins
|
|
gptkbp:HGNC_ID
|
8507
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
oncostatin M
|
|
gptkbp:length
|
252 amino acids
|
|
gptkbp:locatedOnChromosome
|
22q12.2
|
|
gptkbp:memberOf
|
gptkb:interleukin-6_family
|
|
gptkbp:OMIM
|
600419
|
|
gptkbp:producedBy
|
macrophages
monocytes
activated T cells
|
|
gptkbp:recipient
|
gptkb:gp130
oncostatin M receptor
|
|
gptkbp:relatedTo
|
gptkb:interleukin-6
gptkb:leukemia_inhibitory_factor
|
|
gptkbp:structure
|
four-helix bundle
|
|
gptkbp:UniProtID
|
P13725
|
|
gptkbp:bfsParent
|
gptkb:gp130_receptor
|
|
gptkbp:bfsLayer
|
6
|