norepinephrine transporter

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein gptkb:solute_carrier_family
gptkbp:alternativeName	gptkb:NET gptkb:noradrenaline_transporter gptkb:solute_carrier_family_6_member_2
gptkbp:associatedWith	gptkb:depression gptkb:attention_deficit_hyperactivity_disorder gptkb:orthostatic_intolerance
gptkbp:biologicalProcess	neurotransmitter:sodium symporter activity
gptkbp:Entrez_Gene_ID	6530
gptkbp:expressedIn	central nervous system peripheral nervous system
gptkbp:first_cloned	1991
gptkbp:foundIn	neuronal plasma membrane
gptkbp:function	reuptake of dopamine reuptake of norepinephrine
gptkbp:gene	gptkb:SLC6A2
gptkbp:geneType	protein-coding
https://www.w3.org/2000/01/rdf-schema#label	norepinephrine transporter
gptkbp:inhibitedBy	gptkb:tricyclic_antidepressants gptkb:serotonin-norepinephrine_reuptake_inhibitors gptkb:atomoxetine gptkb:reboxetine cocaine
gptkbp:locatedOnChromosome	gptkb:16q12.2 gptkb:chromosome_16
gptkbp:member	gptkb:solute_carrier_family_6
gptkbp:OMIM	163970
gptkbp:orthologInMouse	gptkb:Slc6a2
gptkbp:proteinFamily	integral membrane protein
gptkbp:related_disorder	gptkb:postural_tachycardia_syndrome anxiety hypertension narcolepsy autonomic dysfunction
gptkbp:significance	target for antidepressant drugs target for psychostimulants
gptkbp:structure	12 transmembrane domains
gptkbp:substrate	gptkb:chloride_ion gptkb:sodium_ion dopamine norepinephrine
gptkbp:transportation	dopamine norepinephrine
gptkbp:UniProtID	P23975
gptkbp:bfsParent	gptkb:Ecstasy gptkb:Norepinephrine
gptkbp:bfsLayer	6