|
gptkbp:instanceOf
|
gptkb:growth_factor
gptkb:protein
|
|
gptkbp:alsoKnownAs
|
gptkb:NT-3
|
|
gptkbp:associatedWith
|
gptkb:peripheral_neuropathy
neurodevelopmental disorders
|
|
gptkbp:binds
|
gptkb:TrkC_receptor
TrkB receptor (with lower affinity)
|
|
gptkbp:discoveredIn
|
1990
|
|
gptkbp:expressedIn
|
gptkb:skeletal_muscle
brain
heart
peripheral nervous system
|
|
gptkbp:function
|
promotes survival and differentiation of neurons
supports growth of peripheral and central nervous system neurons
|
|
gptkbp:HGNC_ID
|
8020
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_12p13
|
|
gptkbp:memberOf
|
neurotrophin family
|
|
gptkbp:molecularWeight
|
~27 kDa
|
|
gptkbp:OMIM
|
162662
|
|
gptkbp:product
|
gptkb:NTF3_gene
|
|
gptkbp:relatedTo
|
gptkb:nerve_growth_factor
gptkb:brain-derived_neurotrophic_factor
gptkb:neurotrophin-4
|
|
gptkbp:role
|
gptkb:synaptic_plasticity
neural development
axon guidance
|
|
gptkbp:structure
|
homodimer
|
|
gptkbp:UniProtID
|
P20783
|
|
gptkbp:bfsParent
|
gptkb:NTF3
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
neurotrophic factor 3
|