Statements (31)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
growth factor |
| gptkbp:alsoKnownAs |
gptkb:NT-3
|
| gptkbp:associatedWith |
neurodevelopmental disorders
peripheral neuropathy |
| gptkbp:binds |
gptkb:TrkC_receptor
TrkB receptor (with lower affinity) |
| gptkbp:discoveredIn |
1990
|
| gptkbp:expressedIn |
gptkb:skeletal_muscle
brain heart peripheral nervous system |
| gptkbp:function |
promotes survival and differentiation of neurons
supports growth of peripheral and central nervous system neurons |
| gptkbp:HGNC_ID |
8020
|
| https://www.w3.org/2000/01/rdf-schema#label |
neurotrophic factor 3
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_12p13
|
| gptkbp:memberOf |
neurotrophin family
|
| gptkbp:molecularWeight |
~27 kDa
|
| gptkbp:OMIM |
162662
|
| gptkbp:product |
gptkb:NTF3_gene
|
| gptkbp:relatedTo |
gptkb:nerve_growth_factor
gptkb:brain-derived_neurotrophic_factor gptkb:neurotrophin-4 |
| gptkbp:role |
gptkb:synaptic_plasticity
neural development axon guidance |
| gptkbp:structure |
homodimer
|
| gptkbp:UniProtID |
P20783
|
| gptkbp:bfsParent |
gptkb:NTF3
|
| gptkbp:bfsLayer |
8
|