nephrogenic diabetes insipidus
GPTKB entity
Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instance_of |
gptkb:currency
|
| gptkbp:bfsLayer |
3
|
| gptkbp:bfsParent |
gptkb:currency
|
| gptkbp:associated_with |
genetic mutations
chronic kidney disease |
| gptkbp:can_lead_to |
electrolyte imbalance
dehydration |
| gptkbp:caused_by |
kidney's inability to respond to vasopressin
|
| gptkbp:first_described_by |
1950s
|
| gptkbp:has_achievements |
renal failure
kidney stones urinary tract infections |
| https://www.w3.org/2000/01/rdf-schema#label |
nephrogenic diabetes insipidus
|
| gptkbp:is |
gptkb:central_diabetes_insipidus
gptkb:Company psychogenic polydipsia |
| gptkbp:is_characterized_by |
high urine output
inability to concentrate urine low urine osmolality normal serum osmolality normal serum sodium |
| gptkbp:is_often_used_in |
gptkb:Person
infants females males adults with chronic conditions individuals with genetic predisposition |
| gptkbp:is_popular_in |
rare condition
|
| gptkbp:managed_by |
thiazide diuretics
low-salt diet non-steroidal anti-inflammatory drugs (NSAI Ds) |
| gptkbp:occurs_in |
metabolic disorders
genetic syndromes other endocrine disorders |
| gptkbp:related_to |
hypokalemia
hypercalcemia lithium use |
| gptkbp:social_responsibility |
blood tests
genetic testing MRI of the brain water deprivation test urine concentration tests |
| gptkbp:symptoms |
thirst
excessive urination |
| gptkbp:treatment |
supportive care
diuretics hydration therapy desmopressin (not effective) monitoring of fluid intake |
| gptkbp:type |
primary nephrogenic diabetes insipidus
secondary nephrogenic diabetes insipidus |